# 37degrees

> 37degrees, Inc. is a Chicago-based life-science technology company (founded 2024) building AI-embedded tools for the modern scientist: portable cell-culture systems and OMĒOS, a free-to-start AI-native electronic lab notebook (ELN) for life science and biopharma. Wikidata: Q140290775.

## Products
- [OMĒOS — free AI-native electronic lab notebook (ELN)](https://www.37degrees.io/products/omeos): A modern ELN for life science and biopharma. Automatically collects instrument data, organizes and searches every experiment, enables real-time collaboration, and runs AI analysis in place. Free to get started; paid tiers available.
- [CultureON 100 — portable CO₂ incubator](https://www.37degrees.io/products/physical/cultureon-100/): Portable CO₂ incubator for cell and tissue culture and live-cell transport — maintains 37 °C, CO₂, and humidity outside the lab, with battery operation and remote monitoring.
- [Physical products overview](https://www.37degrees.io/products/physical/): The ON system modules, consumables, and accessories (CultureON, CultureTray SBS, GasPack CO₂, HydraPack, FluidON).

## Guides & comparisons
- [Electronic lab notebooks in 2026: the modern scientist's guide](https://www.37degrees.io/resources/eln-landscape-2026/): Comparison of Benchling, LabArchives, Labguru, eLabFTW, SciNote, RSpace, Colabra, and OMĒOS — the four jobs every ELN does, a positioning chart, and a capability scorecard.
- [Open-source cellular image analysis in 2026](https://www.37degrees.io/resources/cellular-image-analysis-2026/): Field map of CellProfiler, Fiji, ilastik, Cellpose, StarDist, Mesmer, Napari, and foundation models, with a decision matrix.
- [AI agents in the wet lab](https://www.37degrees.io/resources/ai-agents-in-the-wet-lab/): Where lab automation agents earn their keep today and where they still fumble.

## Free interactive tools (no login)
- [Codon Optimizer](https://www.37degrees.io/resources/codon-optimizer/): Free codon optimization with host selection and synthesis constraints (avoid restriction sites, GC bounds, no homopolymers).
- [Plasmid Map Renderer](https://www.37degrees.io/resources/plasmid-map-renderer/): Free plasmid map maker from a GenBank file; export publication-quality SVG.
- [Molarity & Dilution Calculator](https://www.37degrees.io/resources/molarity-dilution/): Molarity, C1V1=C2V2 dilutions, and serial dilutions.
- [qPCR ΔΔCt Calculator](https://www.37degrees.io/resources/qpcr-ddct/): Relative gene expression (fold change) from Ct values via the Livak method.
- [Protein Parameters Calculator](https://www.37degrees.io/resources/protein-parameters/): MW, pI, extinction coefficient, GRAVY from a protein sequence (ProtParam-style).
- [Bioreactor / Perfusion Calculator](https://www.37degrees.io/resources/bioreactor-perfusion/): VVD, dilution rate, residence time, and CSPR for continuous culture.
- [Doubling Time Calculator](https://www.37degrees.io/resources/doubling-time/): Cell-culture doubling time and specific growth rate.
- [Plate Editor](https://www.37degrees.io/resources/plate-editor/): Multi-well plate layout designer and dose-response (EC₅₀/IC₅₀) analyzer.
- [Tm + Restriction Mapper](https://www.37degrees.io/resources/tm-restriction/): Primer melting temperature (nearest-neighbor) and restriction-site mapping.

## Research publications
- [Resources — research publications](https://www.37degrees.io/resources/category/research-publications/): Peer-reviewed papers and posters (TERMIS, Bioengineering MDPI, and others) on portable perfusion and incubation systems.

## Company
- [About 37degrees](https://www.37degrees.io/about/): Company background, mission, and team.
- [Technology](https://www.37degrees.io/technology/): The platform approach behind the products.
- [Contact](https://www.37degrees.io/contactus/): Get in touch.